Description

2-Oxoindoline-5-Carbaldehyde is a versatile and high-value pharmaceutical intermediate and organic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anti-cancer agents, and other biologically active heterocyclic compounds.
• Organic Synthesis Building Block: Used in palladium-catalyzed cross-coupling reactions, reductive amination, and as a starting material for the construction of complex indole and indoline-based scaffolds.
• Agrochemical Research: Serves as a foundational structure for developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Investigated for the development of organic semiconductors, dyes, and photoactive materials due to its conjugated carbonyl-aldehyde system.
• Academic & Contract Research: Essential for medicinal chemistry research, process development, and scale-up activities in university and CRO/CMO settings.

Basic Information

Product Name	2-Oxoindoline-5-Carbaldehyde
CAS No.	612487-62-4
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	5-Formyl-2-indolinone; 5-Formylindolin-2-one; 2-Indolinone-5-carboxaldehyde; 1H-Indole-2,3-dione, 5-formyl- (9CI); 5-Carbaldehyde-2-oxoindoline; Isatin-5-carbaldehyde; 5-Aldehydoisatin
EINECS	Contact for details

Quality Control

Our 2-Oxoindoline-5-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.