Description

5-(Hydroxymethyl)Indolin-2-One is a versatile heterocyclic building block featuring both an indolinone core and a hydroxymethyl functional group. This unique structure makes it a critical intermediate for the synthesis of complex pharmaceutical compounds and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry and the exploration of new chemical spaces.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-(Hydroxymethyl)Indolin-2-One
CAS No.	612487-61-3
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	5-(Hydroxymethyl)-2-indolinone; 5-(Hydroxymethyl)indolin-2-one; 2-Oxo-5-indolinemethanol; 5-Hydroxymethyloxindole; 5-(Hydroxymethyl)-1,3-dihydro-2H-indol-2-one; 5-Indolinemethanol, 2-oxo-; 5-(Hydroxymethyl)-2-indolone
EINECS	Contact for details

Quality Control

Our 5-(Hydroxymethyl)Indolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.