Description

8-Benzenesulfonyl-6-(Pyridin-2-Ylamino)-2,3-Dihydro-1H-Indolizin-5-One is a high-value, synthetically advanced heterocyclic compound that serves as a critical building block in modern pharmaceutical research and development. Its unique molecular architecture, featuring fused indolizine and pyridine rings with a benzenesulfonyl group, makes it a versatile intermediate for constructing complex bioactive molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold or a sophisticated building block for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology Probes: Serves as a starting material for developing selective enzyme inhibitors or molecular probes to study biological pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for investigating new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	8-Benzenesulfonyl-6-(Pyridin-2-Ylamino)-2,3-Dihydro-1H-Indolizin-5-One
CAS No.	612065-29-9
Molecular Formula	C23H19N3O3S
Molecular Weight	417.48 g/mol
Synonyms	6-[(Pyridin-2-yl)amino]-8-(phenylsulfonyl)-2,3-dihydro-1H-indolizin-5-one; 8-(Phenylsulfonyl)-6-(2-pyridinylamino)-2,3-dihydro-1H-indolizin-5-one; 8-Benzenesulfonyl-6-(2-pyridinylamino)-2,3-dihydro-1H-indolizin-5-one; 612065-29-9; 6-(Pyridin-2-ylamino)-8-(phenylsulfonyl)-2,3-dihydro-1H-indolizin-5-one
EINECS	Contact for details

Quality Control

We supply 8-Benzenesulfonyl-6-(Pyridin-2-Ylamino)-2,3-Dihydro-1H-Indolizin-5-One with a standard purity grade suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.