Description

8-Benzenesulfonyl-6-(3,5-Dimethoxyphenylamino)-2,3-Dihydro-1H-Indolizin-5-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex bioactive molecules. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indolizine-based drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function and biological mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for the production of complex, high-value specialty chemicals.
• Academic & Contract Research: Essential for university and CRO laboratories conducting cutting-edge research in heterocyclic chemistry.

Basic Information

Product Name	8-Benzenesulfonyl-6-(3,5-Dimethoxyphenylamino)-2,3-Dihydro-1H-Indolizin-5-One
CAS No.	612065-27-7
Molecular Formula	C22H21N3O5S
Molecular Weight	439.48 g/mol
Synonyms	8-Benzenesulfonyl-6-(3,5-dimethoxyphenylamino)-2,3-dihydro-1H-indolizin-5-one; 6-[(3,5-Dimethoxyphenyl)amino]-8-(phenylsulfonyl)-2,3-dihydro-5H-indolizin-5-one; 5H-Indolizin-5-one, 6-[(3,5-dimethoxyphenyl)amino]-2,3-dihydro-8-(phenylsulfonyl)-; 612065-27-7; 8-Phenylsulfonyl-6-(3,5-dimethoxyanilino)-2,3-dihydro-1H-indolizin-5-one
EINECS	Contact for details

Quality Control

Our 8-Benzenesulfonyl-6-(3,5-Dimethoxyphenylamino)-2,3-Dihydro-1H-Indolizin-5-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.