Description

8-Benzenesulfonyl-6-(4-Methoxyphenylamino)-2,3-Dihydro-1H-Indolizin-5-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new chemical entities (NCEs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Serves as a probe or inhibitor in biochemical assays to study specific enzyme or receptor interactions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex molecules for agrochemical or material science applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	8-Benzenesulfonyl-6-(4-Methoxyphenylamino)-2,3-Dihydro-1H-Indolizin-5-One
CAS No.	612065-25-5
Molecular Formula	C21H18N2O4S
Molecular Weight	394.45 g/mol
Synonyms	8-Benzenesulfonyl-6-(4-methoxyanilino)-2,3-dihydro-1H-indolizin-5-one; 6-[(4-Methoxyphenyl)amino]-8-(phenylsulfonyl)-2,3-dihydro-1H-indolizin-5-one; 5(1H)-Indolizinone, 8-(benzenesulfonyl)-6-[(4-methoxyphenyl)amino]-2,3-dihydro-; CAS 612065-25-5
EINECS	Contact for details

Quality Control

Our 8-Benzenesulfonyl-6-(4-Methoxyphenylamino)-2,3-Dihydro-1H-Indolizin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.