Description

Methyl 5-Oxo-6-(Pyridin-2-Ylamino)-1,2,3,5-Tetrahydroindolizine-8-Carboxylate CAS NO 612065-23-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex indolizine core structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Heterocyclic Compound Synthesis: Serves as a versatile precursor for constructing complex indolizine and fused ring systems.
• Biochemical Research: Potential use as a tool compound or probe in biochemical and pharmacological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodology development.

Basic Information

Product Name	Methyl 5-Oxo-6-(Pyridin-2-Ylamino)-1,2,3,5-Tetrahydroindolizine-8-Carboxylate
CAS No.	612065-23-3
Molecular Formula	C16H15N3O3
Molecular Weight	297.31 g/mol
Synonyms	Methyl 5-oxo-6-(pyridin-2-ylamino)-1,2,3,5-tetrahydroindolizine-8-carboxylate; 8-Carbomethoxy-6-(2-pyridylamino)-1,2,3,5-tetrahydroindolizin-5-one; 612065-23-3; 6-[(Pyridin-2-yl)amino]-1,2,3,5-tetrahydro-5-oxoindolizine-8-carboxylic acid methyl ester; Methyl 6-(2-pyridinylamino)-1,2,3,5-tetrahydro-5-oxoindolizine-8-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Oxo-6-(Pyridin-2-Ylamino)-1,2,3,5-Tetrahydroindolizine-8-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.