Description

Methyl 6-(4-Nitrophenylamino)-5-Oxo-1,2,3,5-Tetrahydroindolizine-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 612065-20-0. This compound is valued for its role as a critical building block in the synthesis of complex heterocyclic molecules, offering precise structural control for research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indolizine-based drug candidates, particularly for research into therapeutic agents.
• Organic Synthesis Building Block: Used in academic and industrial research for constructing complex heterocyclic frameworks due to its reactive functional groups.
• Chemical Research & Development: Serves as a standard or reference compound in method development for analytical chemistry and process optimization studies.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and specialty agrochemicals.
• Material Science: Investigated for the development of organic electronic materials and functional dyes, leveraging its conjugated structure.

Basic Information

Product Name	Methyl 6-(4-Nitrophenylamino)-5-Oxo-1,2,3,5-Tetrahydroindolizine-8-Carboxylate
CAS No.	612065-20-0
Molecular Formula	C20H17N3O5
Molecular Weight	379.37 g/mol
Synonyms	Methyl 6-[(4-nitrophenyl)amino]-5-oxo-1,2,3,5-tetrahydro-8-indolizinecarboxylate; 8H-Indolizine-8-carboxylic acid, 1,2,3,5-tetrahydro-6-[(4-nitrophenyl)amino]-5-oxo-, methyl ester; Methyl 6-(4-nitroanilino)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate; 612065-20-0; 6-(4-Nitrophenylamino)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-(4-Nitrophenylamino)-5-Oxo-1,2,3,5-Tetrahydroindolizine-8-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.