Description

Methyl 5-Oxo-6-Phenylamino-1,2,3,5-Tetrahydroindolizine-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing novel indolizine-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a specialized intermediate in the development of new-generation crop protection agents with unique modes of action.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or photoactive materials due to its conjugated system.

Basic Information

Product Name	Methyl 5-Oxo-6-Phenylamino-1,2,3,5-Tetrahydroindolizine-8-Carboxylate
CAS No.	612065-18-6
Molecular Formula	C20H18N2O3
Molecular Weight	334.37 g/mol
Synonyms	Methyl 5-oxo-6-(phenylamino)-1,2,3,5-tetrahydro-8H-indolizine-8-carboxylate; 8H-Indolizine-8-carboxylic acid, 1,2,3,5-tetrahydro-5-oxo-6-(phenylamino)-, methyl ester; 6-Anilino-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid methyl ester; Methyl 6-anilino-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Oxo-6-Phenylamino-1,2,3,5-Tetrahydroindolizine-8-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.