Description

1,2,3,6-Tetrahydroindolizino[6,7-B]Indol-5-One is a high-purity, advanced pharmaceutical intermediate with the CAS number 612065-16-4. This compound is valued for its complex polyheterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloid-based drug candidates and investigational new drugs (INDs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Employed in the research and synthesis of potential anti-cancer agents targeting specific cellular pathways.
• CNS-Active Compound Synthesis: Serves as a building block for developing novel compounds with potential neurological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and synthesizing novel molecular libraries.

Basic Information

Product Name	1,2,3,6-Tetrahydroindolizino[6,7-B]Indol-5-One
CAS No.	612065-16-4
Molecular Formula	C13H12N2O
Molecular Weight	212.25 g/mol
Synonyms	1,2,3,6-Tetrahydroindolizino[6,7-b]indol-5-one; Indolizino[6,7-b]indol-5(1H)-one, 1,2,3,6-tetrahydro-; 612065-16-4; Tetrahydroindolizinoindolone; CAS 612065-16-4
EINECS	Contact for details

Quality Control

Our production of 1,2,3,6-Tetrahydroindolizino[6,7-B]Indol-5-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.