Description

6-(2-Trifluoromethylphenylamino)-2,3-Dihydro-1H-Indolizin-5-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Serves as a building block in the process development and scale-up of potential Active Pharmaceutical Ingredients.
• Biochemical Research: Employed in the development of chemical probes and inhibitors for biological target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-(2-Trifluoromethylphenylamino)-2,3-Dihydro-1H-Indolizin-5-One
CAS No.	612065-09-5
Molecular Formula	C15H11F3N2O
Molecular Weight	292.26 g/mol
Synonyms	5H-Indolizin-5-one, 2,3-dihydro-6-[[2-(trifluoromethyl)phenyl]amino]-; 6-[(2-Trifluoromethylphenyl)amino]-2,3-dihydro-1H-indolizin-5-one; 6-(2-(Trifluoromethyl)phenylamino)-2,3-dihydroindolizin-5-one; 6-(α,α,α-Trifluoro-o-toluidino)-2,3-dihydro-5H-indolizin-5-one; CAS 612065-09-5
EINECS	Contact for details

Quality Control

Our 6-(2-Trifluoromethylphenylamino)-2,3-Dihydro-1H-Indolizin-5-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.