Description

Cyclohexanol,2-(Phenylethynyl)-,(1R,2S)-(9Ci) is a chiral, non-racemic organic compound featuring a cyclohexanol core substituted with a phenylethynyl group. This specific stereoisomer is valued as a high-purity advanced pharmaceutical intermediate (API intermediate) and a versatile chiral building block in asymmetric synthesis. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and production of potential drug candidates, particularly in areas requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and total synthesis projects.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the synthesis of specialty polymers or organic electronic materials due to its rigid, conjugated phenylethynyl moiety.
• Agrochemical Intermediates: Potential use in the synthesis of chiral active ingredients for crop protection agents.
• Academic and R&D: A valuable reagent for universities and corporate R&D labs exploring new synthetic methodologies and chemical spaces.

Basic Information

Product Name	Cyclohexanol,2-(Phenylethynyl)-,(1R,2S)-(9Ci)
CAS No.	612040-73-0
Molecular Formula	C14H16O
Molecular Weight	200.28 g/mol
Synonyms	(1R,2S)-2-(Phenylethynyl)cyclohexanol; (1R,2S)-2-(2-Phenylethynyl)cyclohexanol; (-)-trans-2-(Phenylethynyl)cyclohexanol; (1R,2S)-rel-2-(Phenylethynyl)cyclohexanol; 2-(Phenylethynyl)cyclohexanol, (1R,2S)-; 2-(2-Phenylethynyl)cyclohexanol, (1R,2S)-rel-; Chiral Phenylethynyl Cyclohexanol Derivative
EINECS	Contact for details

Quality Control

Our production of Cyclohexanol,2-(Phenylethynyl)-,(1R,2S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques including HPLC, GC, and chiral chromatography for precise characterization. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.