Description

3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6,7-Dihydroxy-, Methyl Ester, (3S)- (9Ci) is a chiral, substituted isoquinoline derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its value lies in its stereochemically defined structure and functional groups, which enable the synthesis of complex molecules with high precision. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular applications.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex alkaloids and potential drug candidates targeting specific receptors.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new synthetic methodologies.
• Asymmetric Catalysis Studies: Serves as a substrate or ligand precursor in the development and testing of new chiral catalysts.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Probe Development: Potential starting material for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6,7-Dihydroxy-, Methyl Ester, (3S)- (9Ci)
CAS No.	611239-26-0
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	(3S)-1,2,3,4-Tetrahydro-6,7-dihydroxy-3-isoquinolinecarboxylic acid methyl ester; (S)-Methyl 1,2,3,4-tetrahydro-6,7-dihydroxyisoquinoline-3-carboxylate; 6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester, (3S)-; Tetrahydroisoquinoline derivative; Salsolinol-3-carboxylic acid methyl ester (related analog)
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6,7-Dihydroxy-, Methyl Ester, (3S)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific properties.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.