Description

(1H-Indol-3-Yl)(Piperazin-1-Yl) Methanone is a high-purity organic building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for synthesizing novel bioactive molecules, particularly those targeting central nervous system (CNS) receptors. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery programs. The consistent quality and reliable supply of this intermediate are paramount for accelerating preclinical and clinical development timelines.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential therapeutic agents, including serotonin receptor modulators and kinase inhibitors.
• Chemical Biology Research: Used in the design and synthesis of molecular probes to study protein-ligand interactions and signaling pathways.
• Library Synthesis: Employed in combinatorial and parallel synthesis to create diverse compound libraries for high-throughput screening (HTS).
• Agrochemical Research: Investigated as a precursor for novel crop protection agents with specific biological activity.
• Academic Research: Serves as a standard or starting material in university laboratories for methodological studies in organic synthesis.

Basic Information

Product Name	(1H-Indol-3-Yl)(Piperazin-1-Yl) Methanone
CAS No.	610802-16-9
Molecular Formula	C₁₃H₁₅N₃O
Molecular Weight	229.28 g/mol
Synonyms	1-(1H-Indole-3-carbonyl)piperazine; 1-(1H-Indol-3-ylcarbonyl)piperazine; 1-(Indole-3-carbonyl)piperazine; 1-(Piperazin-1-yl)-1H-indol-3-ylmethanone; 3-(Piperazine-1-carbonyl)-1H-indole; (1H-Indol-3-yl)(piperazin-1-yl)methanone; Piperazine, 1-(1H-indole-3-carbonyl)-; 610802-16-9
EINECS	Contact for details

Quality Control

Our (1H-Indol-3-Yl)(Piperazin-1-Yl) Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.