Description

4-Bromo-5-Isopropyl-1H-Indazole is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of targeted small molecule drugs, especially kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Used as a core scaffold or substituent for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Material Science: Potential precursor for organic electronic materials and functional polymers due to its indazole core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	4-Bromo-5-Isopropyl-1H-Indazole
CAS No.	610796-21-9
Molecular Formula	C10H11BrN2
Molecular Weight	239.11 g/mol
Synonyms	4-Bromo-5-(1-methylethyl)-1H-indazole; 5-Isopropyl-4-bromo-1H-indazole; 1H-Indazole, 4-bromo-5-(1-methylethyl)-; 4-Bromo-5-isopropylindazole; 4-Bromo-5-propan-2-yl-1H-indazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Isopropyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.