Description

6-Fluoro-1-(Piperidin-4-Yl)-1H-Benzo[D]Imidazol-2(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the benzimidazole chemical class. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting neurological and oncological therapeutic areas. Our supply is characterized by stringent quality control, batch-to-batch consistency, and reliable global logistics to support critical development timelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves in the development and scale-up processes for new active pharmaceutical ingredients, especially within the benzimidazole therapeutic class.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological research projects.

Basic Information

Product Name	6-Fluoro-1-(Piperidin-4-Yl)-1H-Benzo[D]Imidazol-2(3H)-One
CAS No.	610323-35-8
Molecular Formula	C₁₂H₁₄FN₃O
Molecular Weight	235.26 g/mol
Synonyms	6-Fluoro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 6-Fluoro-1-piperidin-4-yl-1,3-dihydro-2H-benzimidazol-2-one; 1-(Piperidin-4-yl)-6-fluoro-1H-benzo[d]imidazol-2(3H)-one; 6-Fluoro-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one; 610323-35-8; 6-Fluoro-1-piperidin-4-yl-2-benzimidazolinone; 2H-Benzimidazol-2-one, 6-fluoro-1-(4-piperidinyl)-1,3-dihydro-
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-1-(Piperidin-4-Yl)-1H-Benzo[D]Imidazol-2(3H)-One is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development needs with custom purity grades and can provide materials suitable for research use under cGMP guidelines for advanced projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in amber glass or opaque containers to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.