Description

1-[(5-Methylthien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is a high-purity, non-natural amino acid derivative featuring a piperidine core functionalized with a carboxylic acid and a substituted thiophene sulfonyl group. This compound is a critical pharmaceutical intermediate and building block in modern organic synthesis, valued for its unique structural motifs that enable the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Protease Inhibitor Research: Used in the development of inhibitors for various enzymes due to its carboxylic acid and sulfonamide functionalities.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes and activity-based protein profiling (ABPP) reagents.
• Agrochemical Synthesis: Employed in research for developing new active ingredients with specific biological activity.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-[(5-Methylthien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid
CAS No.	610261-43-3
Molecular Formula	C12H15NO4S2
Molecular Weight	301.38 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[(5-methyl-2-thienyl)sulfonyl]-; 1-(5-Methylthiophene-2-sulfonyl)piperidine-3-carboxylic acid; 1-[(5-Methyl-2-thienyl)sulfonyl]-3-piperidinecarboxylic acid; 1-(5-Methyl-2-thiophenesulfonyl)piperidine-3-carboxylic acid; 1-(5-Methylthiophene-2-sulfonyl)piperidine-3-carboxylic acid; 610261-43-3; 1-(5-Methylthiophene-2-sulfonyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(5-Methylthien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.