Description

1H-Indole-4,5,6-Triol, Octahydro-1-(2-Hydroxyethyl)-, (3Ar,4S,5S,6R,7Ar)-Rel- (9Ci) is a complex, stereochemically defined indole derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound's unique polyhydroxylated and octahydroindole scaffold makes it a valuable chiral building block for the development of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) or metabolic disorder targets.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and other polycyclic compounds due to its multiple stereocenters and functional groups.
• Agrochemical Research: Employed in the synthesis of novel, biologically active compounds for crop protection and pest management applications.
• Chemical Biology Probe Development: Acts as a core structure for creating molecular probes to study enzyme function or biological pathways.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise stereochemistry.

Basic Information

Product Name	1H-Indole-4,5,6-Triol, Octahydro-1-(2-Hydroxyethyl)-, (3Ar,4S,5S,6R,7Ar)-Rel- (9Ci)
CAS No.	609344-58-3
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	rel-(3aR,4S,5S,6R,7aR)-Octahydro-1-(2-hydroxyethyl)-1H-indole-4,5,6-triol; (3aR,4S,5S,6R,7aR)-1-(2-Hydroxyethyl)octahydro-1H-indole-4,5,6-triol; 1-(2-Hydroxyethyl)octahydroindole-4,5,6-triol; Octahydro-1-(2-hydroxyethyl)-1H-indole-4,5,6-triol; CAS 609344-58-3
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the identity, purity, and consistency of this advanced intermediate. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm stereochemical purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our production and quality control processes are designed to support cGMP compliance for applications requiring the highest standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant packs or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.