Description

8-Bromo-3-Methoxyisoquinoline is a versatile halogenated isoquinoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the bromine atom offers a reactive site for cross-coupling reactions, and the methoxy-substituted isoquinoline core provides a privileged scaffold for pharmaceutical development. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block for developing new active ingredients for crop protection and pest management.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays and diagnostic tool development due to its fluorescent isoquinoline core.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in palladium-catalyzed cross-coupling reactions like Suzuki or Buchwald-Hartwig amination.
• Ligand Synthesis: Can be utilized to develop novel chelating ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	8-Bromo-3-Methoxyisoquinoline
CAS No.	608515-50-0
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	8-Bromo-3-methoxyisoquinoline; 3-Methoxy-8-bromoisoquinoline; Isoquinoline, 8-bromo-3-methoxy-; 8-Bromo-3-methoxy-isoquinoline; 608515-50-0; 8-Br-3-MeO-isoquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.