Description

3-(5-Formylthiophen-2-Yl)Benzoic Acid is a high-purity organic building block featuring both a carboxylic acid and an aldehyde functional group on a biaryl thiophene scaffold. This compound is critical for advanced research and development in pharmaceutical chemistry, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery and functional material synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its unique heterocyclic structure.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of conductive polymers and organic electronic materials due to the thiophene moiety.
• Ligand and Catalyst Development: The aldehyde and acid groups allow for derivatization into chelating ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Chemical Biology Probe Synthesis: Utilized in creating fluorescent tags or affinity probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	3-(5-Formylthiophen-2-Yl)Benzoic Acid
CAS No.	606970-74-5
Molecular Formula	C12H8O3S
Molecular Weight	232.26 g/mol
Synonyms	5-(3-Carboxyphenyl)thiophene-2-carboxaldehyde; 3-(5-Formyl-2-thienyl)benzoic Acid; 2-Thiophenecarboxaldehyde, 5-(3-carboxyphenyl)-; Benzoic acid, 3-(5-formyl-2-thienyl)-; [1,1'-Biphenyl]-3-carboxylic acid, 4'-formyl-2'-thio- (related structure); TPC-Aldehyde (common abbreviation); 3-(Thiophen-2-yl)benzoic acid-5-carboxaldehyde derivative
EINECS	Contact for details

Quality Control

Our 3-(5-Formylthiophen-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for purity, impurities, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and light-sensitive (store away from light), prolonged exposure to air or light should be avoided. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.