Description

6-(4-Bromo-2-Chlorophenylamino)-7-Fluoro-1H-Benzo[D]Imidazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme or receptor pathways.
• Biochemical Research: Used as a reference standard or a building block in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• API Development: Serves as a core scaffold for the development of new benzimidazole-derived active pharmaceutical ingredients with potential therapeutic applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up production under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for exploratory synthetic chemistry and pharmacological research.

Basic Information

Product Name	6-(4-Bromo-2-Chlorophenylamino)-7-Fluoro-1H-Benzo[D]Imidazole-5-Carboxylic Acid
CAS No.	606144-01-8
Molecular Formula	C14H8BrClFN3O2
Molecular Weight	384.59 g/mol
Synonyms	6-[(4-Bromo-2-chlorophenyl)amino]-7-fluoro-1H-benzimidazole-5-carboxylic acid; 7-Fluoro-6-((4-bromo-2-chlorophenyl)amino)-1H-benzo[d]imidazole-5-carboxylic acid; 606144-01-8; Benzoimidazole-5-carboxylic acid, 6-[(4-bromo-2-chlorophenyl)amino]-7-fluoro-1H-; CAS 606144-01-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (typically ≥97% by HPLC), to ensure consistency and reliability for critical research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is soluble in strong acids and organic solvents; handle with appropriate precautions in a fume hood.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.