Description

Propanamide, n-[4-[2,3-Dihydro-1-(2-Methyl-1-Oxopropyl)-1H-Indol-5-Yl]-5-Methyl-2-Thiazolyl]-2-Methyl- (9Ci) CAS NO 606121-91-9 is a high-purity, specialized organic compound belonging to the indole-thiazole chemical class, serving as a critical building block in advanced pharmaceutical research and development. Its complex molecular architecture makes it an invaluable intermediate for synthesizing novel bioactive molecules, particularly in the discovery of enzyme inhibitors and receptor modulators. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical sectors for creating next-generation therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays and high-throughput screening (HTS) campaigns to identify potential drug leads.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies, enabling the optimization of potency, selectivity, and pharmacokinetic properties.
• Agrochemical Development: Investigated as an intermediate for novel crop protection agents, including fungicides and insecticides, leveraging its heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting custom synthesis and scale-up projects for client-specific molecular entities.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	Propanamide, n-[4-[2,3-Dihydro-1-(2-Methyl-1-Oxopropyl)-1H-Indol-5-Yl]-5-Methyl-2-Thiazolyl]-2-Methyl- (9Ci)
CAS No.	606121-91-9
Molecular Formula	C21H25N3O2S
Molecular Weight	383.51 g/mol
Synonyms	N-[4-(2,3-Dihydro-1-(2-methylpropanoyl)-1H-indol-5-yl)-5-methyl-1,3-thiazol-2-yl]-2-methylpropanamide; 2-Methyl-N-[4-[1-(2-methylpropanoyl)-2,3-dihydro-1H-indol-5-yl]-5-methyl-1,3-thiazol-2-yl]propanamide; UNII-6G6P5UC8J6; 6G6P5UC8J6; Propanamide, N-[4-[2,3-dihydro-1-(2-methyl-1-oxopropyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-2-methyl-; BDBM50164957; AKOS015915889; AS-57811
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under a strict quality management system. We employ state-of-the-art analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment, ensuring full traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.