Description

2-Thiophenecarboxylicacid,1-(4-Methoxyphenyl)-2-Oxo-2-[[(Tetrahydro-2-Furanyl)Methyl]Amino]Ethylester(9Ci) is a sophisticated organic compound featuring a thiophene carboxylic acid ester core linked to a 4-methoxyphenyl and a tetrahydrofuran-derived amine moiety. This unique molecular architecture makes it a valuable advanced intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams requiring high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the thiophene and methoxyphenyl groups can contribute to specific biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing more complex molecules in academic and industrial research laboratories.
• Material Science: Potential intermediate for the development of organic electronic materials or specialty polymers due to its conjugated thiophene system.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	2-Thiophenecarboxylicacid,1-(4-Methoxyphenyl)-2-Oxo-2-[[(Tetrahydro-2-Furanyl)Methyl]Amino]Ethylester(9Ci)
CAS No.	606114-63-0
Molecular Formula	C19H21NO5S
Molecular Weight	375.44 g/mol
Synonyms	1-(4-Methoxyphenyl)-2-oxo-2-[[(tetrahydro-2-furanyl)methyl]amino]ethyl 2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 1-(4-methoxyphenyl)-2-oxo-2-[[(tetrahydro-2-furanylmethyl)amino]ethyl ester; Ethyl 1-(4-methoxyphenyl)-2-oxo-2-((tetrahydrofuran-2-ylmethyl)amino)ethyl thiophene-2-carboxylate; (9CI) Identifier; CAS 606114-63-0; Advanced Thiophene Ester Intermediate; Tetrahydrofurfurylamine Thiophene Ester Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development under quality agreements and can discuss cGMP-compliant manufacturing for later-stage projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.