Description

Piperidine, 2-Methyl-1-[[[1-[2-Oxo-2-(1-Pyrrolidinyl)Ethyl]-1H-Benzimidazol-2-Yl]Thio]Acetyl]- (9Ci) is a sophisticated heterocyclic organic compound featuring a piperidine core linked to a benzimidazole-thioacetyl-pyrrolidinone moiety. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel active ingredients. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

This specialized intermediate is designed for high-value synthesis in regulated industries. Its primary applications include:

• Pharmaceutical Intermediate: Serving as a key building block in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities (NCEs).
• Reference Standard: Utilized as an analytical standard for method development and quality control in the production of related active pharmaceutical ingredients (APIs).
• Biochemical Probe Synthesis: A precursor for creating specialized molecular tools used to study biological mechanisms and protein interactions.

Basic Information

Product Name	Piperidine, 2-Methyl-1-[[[1-[2-Oxo-2-(1-Pyrrolidinyl)Ethyl]-1H-Benzimidazol-2-Yl]Thio]Acetyl]- (9Ci)
CAS No.	606109-68-6
Molecular Formula	C22H28N4O3S
Molecular Weight	428.55 g/mol
Synonyms	2-Methyl-1-({[1-(2-oxo-2-pyrrolidin-1-ylethyl)-1H-benzimidazol-2-yl]sulfanyl}acetyl)piperidine; 1-[(1-{2-Oxo-2-[(2S)-2-pyrrolidinyl]ethyl}-1H-benzimidazol-2-yl)thio]acetyl]-2-methylpiperidine; 2-Methyl-1-({[1-(2-oxo-2-pyrrolidin-1-ylethyl)-1H-1,3-benzodiazol-2-yl]sulfanyl}acetyl)piperidine; (9CI) Piperidine, 2-methyl-1-[[[1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1H-benzimidazol-2-yl]thio]acetyl]-; CAS 606109-68-6
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing results from HPLC, NMR, and mass spectrometry. We support development projects with custom synthesis and purity grades tailored to specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.