Description

1H-Benzimidazole-1-Acetamide,n-Cyclopentyl-2-[[2-(3-Methyl-1-Piperidinyl)-2-Oxoethyl]Thio]-(9Ci) is a sophisticated, high-purity organic compound with the CAS number 606109-27-7, serving as a critical advanced pharmaceutical intermediate in modern drug discovery and development. Its complex molecular architecture, featuring a benzimidazole core linked to a substituted acetamide via a thioether bridge, makes it a valuable scaffold for constructing potent and selective bioactive molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in areas requiring targeted molecular interactions.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially for targeted therapies.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its potential binding affinity, relevant for antiviral or anticancer drug discovery.
• Kinase Inhibitor Scaffold: Serves as a core structure for designing and optimizing kinase inhibitors, a major class of drugs for oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized in academic and industrial research to study enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Preclinical Development: Employed in the early-stage development of active pharmaceutical ingredients (APIs) to establish proof-of-concept and initial safety profiles.

Basic Information

Product Name	1H-Benzimidazole-1-Acetamide,n-Cyclopentyl-2-[[2-(3-Methyl-1-Piperidinyl)-2-Oxoethyl]Thio]-(9Ci)
CAS No.	606109-27-7
Molecular Formula	C22H30N4O2S
Molecular Weight	414.57 g/mol
Synonyms	N-Cyclopentyl-2-({2-[(3-methylpiperidin-1-yl)carbonyl]ethyl}sulfanyl)-1H-benzimidazole-1-acetamide; 1H-Benzimidazole-1-acetamide, N-cyclopentyl-2-[[2-(3-methyl-1-piperidinyl)-2-oxoethyl]thio]-; 606109-27-7; UNII-9Q5Q9P4I4M; 9Q5Q9P4I4M; SCHEMBL218062; AKOS040759623; ZINC000103074511
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity essential for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with internal quality standards and facilitating regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.