Description

Acetamide, n-(3-Chloro-4-Fluorophenyl)-2-[(1,4-Dihydro-5,6-Dimethyl-4-Oxothieno[2,3-D]Pyrimidin-2-Yl)Thio]- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Research and development teams in the global pharmaceutical and biotechnology sectors need this material for drug discovery programs, process development, and the production of candidate compounds for pre-clinical and clinical studies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting specific enzyme pathways.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its unique thienopyrimidine core.
• API Synthesis: Incorporated into the final chemical structure of potential new chemical entities (NCEs) under investigation for various therapeutic applications.
• Biochemical Research: Employed as a tool compound in biochemical assays to study biological mechanisms and identify potential drug targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Acetamide, n-(3-Chloro-4-Fluorophenyl)-2-[(1,4-Dihydro-5,6-Dimethyl-4-Oxothieno[2,3-D]Pyrimidin-2-Yl)Thio]- (9Ci)
CAS No.	606108-58-1
Molecular Formula	C16H13ClFN3O2S2
Molecular Weight	397.88 g/mol
Synonyms	N-(3-Chloro-4-fluorophenyl)-2-[(5,6-dimethyl-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]acetamide; 2-(((5,6-Dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio))-N-(3-chloro-4-fluorophenyl)acetamide; Acetamide, N-(3-chloro-4-fluorophenyl)-2-[(5,6-dimethyl-4-oxo-1H-thieno[2,3-d]pyrimidin-2-yl)thio]-; 606108-58-1; Thieno[2,3-d]pyrimidine acetamide derivative
EINECS	Contact for details

Quality Control

Our Acetamide, n-(3-Chloro-4-Fluorophenyl)-2-[(1,4-Dihydro-5,6-Dimethyl-4-Oxothieno[2,3-D]Pyrimidin-2-Yl)Thio]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical methods (HPLC, NMR, MS) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.