Description

2-(1,3-Dioxolan-2-Yl)-5-Thiazolecarboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, combining a thiazole core with a protected aldehyde functionality via a dioxolane group, making it a versatile synthon for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic semiconductors and conductive polymers due to its electron-rich heterocyclic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular scaffold.

Basic Information

Product Name	2-(1,3-Dioxolan-2-Yl)-5-Thiazolecarboxylic Acid
CAS No.	603999-23-1
Molecular Formula	C7H7NO4S
Molecular Weight	201.20 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-(1,3-dioxolan-2-yl)-; 2-(1,3-Dioxolan-2-yl)thiazole-5-carboxylic acid; 2-(1,3-Dioxolan-2-yl)-1,3-thiazole-5-carboxylic acid; 2-(Dioxolan-2-yl)thiazole-5-carboxylic acid; Thiazole-5-carboxylic acid, 2-(1,3-dioxolan-2-yl)-; 603999-23-1; AKOS005258065
EINECS	Contact for details

Quality Control

Every batch of 2-(1,3-Dioxolan-2-Yl)-5-Thiazolecarboxylic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.