Description

Acetamide, n-Cyclopropyl-2-[(8-Fluoro-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]- (9Ci) is a sophisticated heterocyclic organic compound featuring a fused triazinoindole core, designed for advanced research and development applications. This high-value chemical building block is critical for medicinal chemistry programs, enabling the synthesis of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel therapeutic targets.
• Fine Chemical Synthesis: Integral in multi-step organic synthesis for creating complex, high-value molecules in milligram to kilogram scales for preclinical and early-phase clinical trials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Acetamide, n-Cyclopropyl-2-[(8-Fluoro-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]- (9Ci)
CAS No.	603948-18-1
Molecular Formula	C16H14FN5OS
Molecular Weight	343.38 g/mol
Synonyms	N-Cyclopropyl-2-[(8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide; 2-((8-Fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-N-cyclopropylacetamide; 603948-18-1; SCHEMBL21828027; AKOS040745623; ZINC000003869777; A1-00326; FT-0777927.
EINECS	Contact for details

Quality Control

Every batch of Acetamide, n-Cyclopropyl-2-[(8-Fluoro-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.