Description

Piperidine, 1-[[(8-Fluoro-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]Acetyl]-4-Methyl- (9Ci) is a sophisticated heterocyclic compound designed for advanced research and development. This molecule is of significant interest due to its complex fused-ring structure, which incorporates piperidine, indole, and triazine motifs, making it a valuable pharmacological research intermediate. It is primarily sought by pharmaceutical R&D teams and contract research organizations (CROs) focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore biological activity, particularly targeting central nervous system (CNS) or oncological pathways.
• Biochemical Tool Compound: Acts as a probe or inhibitor in enzymatic assays and target validation studies within academic and industrial labs.
• Preclinical Development: Employed in the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology evaluations.
• High-Throughput Screening (HTS): Included in specialized compound libraries for screening against novel biological targets.
• Process Chemistry Scale-Up: Used for developing and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Piperidine, 1-[[(8-Fluoro-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]Acetyl]-4-Methyl- (9Ci)
CAS No.	603948-15-8
Molecular Formula	C20H22FN5OS
Molecular Weight	407.49 g/mol
Synonyms	1-[[(8-Fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetyl]-4-methylpiperidine; 4-Methyl-1-[(8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanylacetyl]piperidine; 1-[(8-Fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanylacetyl]-4-methylpiperidine; (8-Fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)acetic acid 4-methylpiperidide; CAS 603948-15-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes. We support development under cGMP guidelines where required for preclinical and clinical stage materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.