Description

Piperidine, 4-Methyl-1-[[[8-(1-Methylethyl)-2H-1,2,4-Triazino[5,6-B]Indol-3-Yl]Thio]Acetyl]- (9Ci) is a sophisticated heterocyclic organic compound that serves as a critical pharmacological intermediate and research chemical. Its complex molecular architecture, featuring fused piperidine, triazine, and indole rings, makes it a valuable scaffold for the development of novel bioactive molecules. This compound is primarily utilized by pharmaceutical R&D organizations and contract research organizations (CROs) engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Biochemical Tool Compound: Employed in in vitro assays to investigate specific biological pathways and protein interactions.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	Piperidine, 4-Methyl-1-[[[8-(1-Methylethyl)-2H-1,2,4-Triazino[5,6-B]Indol-3-Yl]Thio]Acetyl]- (9Ci)
CAS No.	603947-29-1
Molecular Formula	C20H23N5OS
Molecular Weight	389.50 g/mol
Synonyms	4-Methyl-1-[[[8-(1-methylethyl)-2H-1,2,4-triazino[5,6-b]indol-3-yl]thio]acetyl]piperidine; 1-[2-([8-Isopropyl-2H-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanyl)acetyl]-4-methylpiperidine; 4-Methyl-1-({[8-(propan-2-yl)-2H-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanyl}acetyl)piperidine; CAS 603947-29-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support cGMP compliance for materials intended for pharmaceutical development and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.