Description

Piperidine, 1-[[(8-Ethyl-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]Acetyl]- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• API Development: Integral to the process development and scale-up of new active pharmaceutical ingredients, especially for complex small molecules.
• Oncology Drug Discovery: Employed in the research of potential anticancer agents due to its fused triazinoindole-piperidine structure.
• Biochemical Research: May be used as a reference standard or inhibitor in biochemical assays to study specific biological targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	Piperidine, 1-[[(8-Ethyl-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]Acetyl]- (9Ci)
CAS No.	603946-64-1
Molecular Formula	C21H25N5OS
Molecular Weight	395.52 g/mol
Synonyms	1-[[(8-Ethyl-5-Methyl-5H-1,2,4-Triazino[5,6-b]indol-3-yl)thio]acetyl]piperidine; 1-[(8-Ethyl-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetyl]piperidine; 603946-64-1; 1-({[8-Ethyl-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanyl}acetyl)piperidine; Piperidine, 1-[[(8-ethyl-5-methyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]acetyl]-; SCHEMBL2188010; AKOS040759232; ZINC000003870755
EINECS	Contact for details

Quality Control

Our Piperidine, 1-[[(8-Ethyl-5-Methyl-5H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]Acetyl]- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.