Description

2-Thiophenepropanoicacid,α-Amino-5-Ethyl-,Ethylester(9Ci) CAS NO 603945-33-1 is a specialized thiophene-based amino acid ester derivative, serving as a critical chiral building block in advanced organic synthesis. Its molecular structure, featuring both a thiophene ring and a protected amino acid moiety, makes it a valuable intermediate for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Peptidomimetics Research: Serves as a non-natural amino acid analog in the design and synthesis of peptide mimics for drug discovery.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Material Science Precursor: Acts as a starting material for the synthesis of functionalized polymers and organic electronic materials.
• Academic and Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Item	Detail
Product Name	2-Thiophenepropanoicacid,α-Amino-5-Ethyl-,Ethylester(9Ci)
CAS No.	603945-33-1
Molecular Formula	C11H17NO2S
Molecular Weight	227.32 g/mol
Synonyms	Ethyl 2-amino-3-(5-ethylthiophen-2-yl)propanoate; α-Amino-5-ethyl-2-thiophenepropanoic acid ethyl ester; 2-Thiophenepropanoic acid, α-amino-5-ethyl-, ethyl ester; 5-Ethyl-2-thienylalanine ethyl ester; Ethyl 3-(5-ethyl-2-thienyl)-L-alaninate (and related stereoisomers); (S)-Ethyl 2-amino-3-(5-ethylthiophen-2-yl)propanoate; Amino acid ester thiophene derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Thiophenepropanoicacid,α-Amino-5-Ethyl-,Ethylester(9Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.