Description

6-Isoquinolinepropanoicacid, α-Amino-(9Ci) is a high-purity, non-natural amino acid derivative featuring an isoquinoline moiety. This compound is a critical chiral building block in modern organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Peptidomimetic Design: Used to incorporate rigid, aromatic scaffolds into peptide analogs to enhance metabolic stability and receptor binding affinity.
• Chemical Biology Research: Employed as a probe or building block in the study of enzyme mechanisms and protein-ligand interactions.
• Ligand Synthesis for Catalysis: Acts as a precursor for creating novel chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Advanced Material Development: Investigated for the synthesis of functionalized polymers and organic electronic materials due to its conjugated aromatic system.

Basic Information

Product Name	6-Isoquinolinepropanoicacid, α-Amino-(9Ci)
CAS No.	603941-04-4
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25 g/mol
Synonyms	α-Amino-6-isoquinolinepropanoic acid; 2-Amino-3-(6-isoquinolyl)propanoic acid; (S)-2-Amino-3-(isoquinolin-6-yl)propanoic acid (if applicable); 6-Isoquinolinylalanine; 3-(Isoquinolin-6-yl)-L-alanine; (2S)-2-Azaniumyl-3-(isoquinolin-6-yl)propanoate; Amino(6-isoquinolyl)propionic acid
EINECS	Contact for details

Quality Control

Our 6-Isoquinolinepropanoicacid, α-Amino-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) confirming identity, purity, and specifications is provided with every shipment to ensure it meets the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (for specified enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.