Description

1-[(4-Chlorophenyl)Sulfonyl]Indole-3-Carbaldehyde is a high-purity, synthetically valuable organic building block characterized by its indole core functionalized with a chlorophenylsulfonyl group and an aldehyde. This compound matters as a critical intermediate for advanced organic synthesis, enabling the construction of complex molecules with potential biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole scaffold.
• Organic Synthesis Building Block: The reactive aldehyde and sulfonyl groups make it versatile for cross-coupling reactions, condensations, and heterocycle formation.
• Material Science Precursor: Employed in the research of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	1-[(4-Chlorophenyl)Sulfonyl]Indole-3-Carbaldehyde
CAS No.	602330-20-1
Molecular Formula	C15H10ClNO3S
Molecular Weight	319.76 g/mol
Synonyms	1-(4-Chlorobenzenesulfonyl)-1H-indole-3-carboxaldehyde; 3-Formyl-1-(4-chlorophenylsulfonyl)indole; 1H-Indole-3-carboxaldehyde, 1-[(4-chlorophenyl)sulfonyl]-; 1-(p-Chlorophenylsulfonyl)indole-3-carbaldehyde; 1-(4-Chlorophenylsulfonyl)indole-3-carboxaldehyde; 1-(4-Chlorobenzenesulfonyl)indole-3-carbaldehyde; 3-Carbaldehyde-1-(4-chlorophenylsulfonyl)indole; 602330-20-1
EINECS	Contact for details

Quality Control

Our 1-[(4-Chlorophenyl)Sulfonyl]Indole-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.