Description

5-Bromo-3-(2-(4-Fluorophenyl)-2-Oxoethylidine)-1,3-Dihydroindol-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel small-molecule drug candidates, especially in oncology and central nervous system (CNS) research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated indole core structure.
• Organic Synthesis Building Block: Employed in complex organic reactions, including cross-coupling and cyclization, to construct sophisticated heterocyclic compounds.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding activities.
• Material Science Research: Investigated as a potential monomer or additive for creating specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	5-Bromo-3-(2-(4-Fluorophenyl)-2-Oxoethylidine)-1,3-Dihydroindol-2-One
CAS No.	601487-96-1
Molecular Formula	C₁₆H₉BrFNO₂
Molecular Weight	346.15 g/mol
Synonyms	5-Bromo-3-[(4-fluorophenyl)carbonylmethylene]-2-indolinone; 5-Bromo-3-(2-(4-fluorophenyl)-2-oxoethylidene)indolin-2-one; 5-Bromo-3-(4-fluorobenzoylmethylene)-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 5-bromo-3-[(4-fluorophenyl)carbonylmethylene]-1,3-dihydro-; 5-Bromo-3-(4-fluorobenzoyl)methyleneindolin-2-one; 5-Bromo-3-(2-oxo-2-(4-fluorophenyl)ethylidene)indolin-2-one
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-(2-(4-Fluorophenyl)-2-Oxoethylidine)-1,3-Dihydroindol-2-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with industry standards for advanced intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.