Description

(4-Amino-3-Chloro-5-(Trifluoromethyl)Phenyl)Methanol (Wxg00387) is a high-purity, multifunctional aromatic building block characterized by its amino, chloro, and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced, high-value molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring sophisticated chemical synthesis, such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production, need this material for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its unique halogenated structure contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and functional handles.
• Polymer & Resin Modifier: Employed to introduce amino and hydroxyl functionalities into polymer chains, enhancing properties like adhesion, cross-linking density, and chemical resistance in specialty coatings and composites.
• Organic Synthesis Reagent: Acts as a versatile synthon in medicinal and combinatorial chemistry for constructing complex molecular architectures via reactions at the amino, hydroxyl, and aromatic chloro groups.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments, where the trifluoromethyl and amino groups can alter color properties and lightfastness.

Basic Information

Item	Details
Product Name	(4-Amino-3-Chloro-5-(Trifluoromethyl)Phenyl)Methanol (Wxg00387)
CAS No.	600725-44-8
Molecular Formula	C8H7ClF3NO
Molecular Weight	225.60 g/mol
Synonyms	[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]methanol; 3-Chloro-4-amino-5-(trifluoromethyl)benzyl alcohol; 2-Chloro-6-(hydroxymethyl)-4-(trifluoromethyl)aniline; 4-(Aminomethyl)-2-chloro-α,α,α-trifluoro-m-cresol; WXG00387; Benzenemethanol, 4-amino-3-chloro-5-(trifluoromethyl)-; (4-Amino-3-chloro-α,α,α-trifluoro-m-tolyl)methanol
EINECS	Contact for details

Quality Control

Our (4-Amino-3-Chloro-5-(Trifluoromethyl)Phenyl)Methanol is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.