Description

Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-n-[5-(Trifluoromethyl)-1,3,4-Thiadiazol-2-Yl]- (9Ci) is a high-value, multi-heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical research and development. Its complex molecular architecture, featuring fused thiophene and thiadiazole rings with chloro and trifluoromethyl substituents, makes it a versatile building block for creating novel molecules with targeted properties. This compound is primarily sought after by pharmaceutical, agrochemical, and material science R&D teams for the synthesis of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for developing small molecule therapeutics targeting specific enzymes or receptors.
• Agrochemical Research: Used in creating advanced active ingredients for next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole and benzothiophene motifs.
• Material Science: Building block for organic electronic materials, such as semiconductors or charge-transport layers, due to its conjugated system and potential for fine-tuning electronic properties.
• Chemical Biology Probe Development: Serves as a core scaffold for designing molecular probes to study biological pathways and protein interactions.
• Ligand Synthesis in Catalysis: Used to develop novel, complex ligands for transition metal catalysts in asymmetric synthesis and other specialized reactions.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-n-[5-(Trifluoromethyl)-1,3,4-Thiadiazol-2-Yl]- (9Ci)
CAS No.	600122-35-8
Molecular Formula	C₁₂H₅ClF₃N₄OS₂
Molecular Weight	380.77 g/mol
Synonyms	3-Chloro-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide; 3-Chloro-1-benzothiophene-2-carboxylic acid [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]amide; 3-Chloro-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)benzo[b]thiophene-2-carboxamide; CAS 600122-35-8; Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-; 3-Chloro-N-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)benzo[b]thiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-n-[5-(Trifluoromethyl)-1,3,4-Thiadiazol-2-Yl]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and can be tailored to meet specific client requirements for research or GLP-compliant development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.