Description

(Z)-5-Mercapto-3-Pentenoic Acid is a specialized, high-purity organic compound featuring both a thiol (mercapto) and a carboxylic acid functional group on an unsaturated carbon chain. This unique bifunctional structure makes it a valuable versatile building block for synthesizing complex molecules in advanced research and fine chemical production. It is primarily sought after by pharmaceutical researchers and specialty chemical manufacturers for applications in drug discovery, material science, and the synthesis of flavor and fragrance intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring thiol or disulfide linkages.
• Peptide Mimetics & Conjugation: Used in the synthesis of peptide analogs and for the site-specific modification of biomolecules via thiol-click chemistry.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating polymers with specific redox or adhesive properties.
• Flavor & Fragrance Synthesis: An intermediate in the production of complex sulfur-containing compounds that contribute to savory or tropical notes.
• Chemical Research: A valuable reagent in organic synthesis for Michael addition reactions and the construction of heterocyclic compounds.
• Ligand & Catalyst Development: Used to prepare chelating ligands for metal catalysis in asymmetric synthesis.

Basic Information

Product Name	(Z)-5-Mercapto-3-Pentenoic Acid
CAS No.	69962-06-7
Molecular Formula	C5H8O2S
Molecular Weight	132.18 g/mol
Synonyms	(Z)-5-Sulfanylpent-3-enoic acid; (5Z)-5-Mercapto-3-pentenoic acid; 3-Pentenoic acid, 5-mercapto-, (Z)-; 5-Mercapto-3-pentenoic acid (Z)-isomer; cis-5-Mercapto-3-pentenoic acid; 5-SH-3-pentenoic acid
EINECS	Contact for details

Quality Control

Our (Z)-5-Mercapto-3-Pentenoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems support development and cGMP manufacturing requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from heat and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
(Z)-Isomer Content (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.