Description

1-[3-(3,5-Dinitrobenzoylamino)Butyl]-2-Methyl-1H-Indole-3-Carboxylic Acid Ethyl Ester is a high-purity, complex organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a specialized building block in the development of novel pharmacologically active molecules, particularly those targeting specific enzymatic pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially within indole-based compound libraries.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems due to its reactive functional groups (ester, amide, nitro).
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for investigating biological targets and mechanisms.
• Contract Research & Manufacturing (CRMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules.
• Academic Research: Used in university laboratories for methodological development and the exploration of new synthetic routes.

Basic Information

Product Name	1-[3-(3,5-Dinitrobenzoylamino)Butyl]-2-Methyl-1H-Indole-3-Carboxylic Acid Ethyl Ester
CAS No.	69924-48-7
Molecular Formula	C24H26N4O7
Molecular Weight	482.49 g/mol
Synonyms	Ethyl 1-[3-[(3,5-dinitrobenzoyl)amino]butyl]-2-methyl-1H-indole-3-carboxylate; 2-Methyl-1-[3-[(3,5-dinitrobenzoyl)amino]butyl]-1H-indole-3-carboxylic Acid Ethyl Ester; 1H-Indole-3-carboxylic acid, 1-[3-[(3,5-dinitrobenzoyl)amino]butyl]-2-methyl-, ethyl ester; Ethyl 2-methyl-1-[3-(3,5-dinitrobenzamido)butyl]indole-3-carboxylate; 69924-48-7; DNBIE; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-[3-(3,5-Dinitrobenzoylamino)Butyl]-2-Methyl-1H-Indole-3-Carboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for research-grade intermediates. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.