Description

2-[(1-Ethyl-2-Methyl-1H-Indol-3-Yl)Carbonyl]-3-Pyridinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and serves as a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step manufacturing process of complex target molecules for clinical development.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Production: A valuable building block for custom synthesis and contract manufacturing organizations (CMOs) serving the pharma sector.

Basic Information

Product Name	2-[(1-Ethyl-2-Methyl-1H-Indol-3-Yl)Carbonyl]-3-Pyridinecarboxylic Acid
CAS No.	69898-42-6
Molecular Formula	C18H16N2O3
Molecular Weight	308.33 g/mol
Synonyms	3-Pyridinecarboxylic acid, 2-[(1-ethyl-2-methyl-1H-indol-3-yl)carbonyl]-; 2-(1-Ethyl-2-methylindole-3-carbonyl)nicotinic acid; Nicotinic acid, 2-(1-ethyl-2-methylindol-3-ylcarbonyl)-; 69898-42-6; 2-(1-Ethyl-2-methyl-1H-indole-3-carbonyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-[(1-Ethyl-2-Methyl-1H-Indol-3-Yl)Carbonyl]-3-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.