Description

Dl-Serine (3,3-D2) CAS NO 69872-54-4 is a stable isotope-labeled analog of the amino acid serine, specifically deuterated at the 3,3-positions. This compound is essential for advanced research applications where precise molecular tracking and quantification are required. It is primarily utilized by analytical scientists and researchers in the fields of pharmaceutical development, metabolic studies, and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Internal standard for the quantitative analysis of serine and related metabolites via LC-MS/MS and GC-MS.
• Tracer compound in metabolic pathway and pharmacokinetic studies to investigate drug metabolism and nutrient utilization.
• Critical reagent in the synthesis of deuterated peptides and proteins for NMR spectroscopy, enhancing structural resolution.
• Use in proteomics and biomarker discovery research for accurate mass spectrometry-based quantification.
• Substrate for enzymatic studies to understand reaction mechanisms without interference from proton exchange.
• Building block for manufacturing isotopically labeled active pharmaceutical ingredients (APIs) for clinical research.

Basic Information

Product Name	Dl-Serine (3,3-D2)
CAS No.	69872-54-4
Molecular Formula	C₃H₅D₂NO₃
Molecular Weight	107.10 g/mol
Synonyms	DL-Serine-3,3-d2; (±)-Serine-3,3-d2; Serine-d2 (3,3); 2-Amino-3,3-dideuterio-3-hydroxypropanoic Acid; 3-Hydroxy-2-aminopropionic-3,3-d2 Acid; (RS)-Serine-3,3-d2; DL-3,3-Dideuteroserine; Racemic Serine-3,3-d2
EINECS	Contact for details

Quality Control

Our Dl-Serine (3,3-D2) is manufactured under strict quality systems to ensure high isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and absence of specific impurities. We adhere to cGMP principles for research-grade materials, ensuring traceability and consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.