Description

3-(Trimethylsiloxy)-1,3,5(10),9(11)-Estratetren-17-One is a high-purity, advanced steroid intermediate featuring a strategically protected hydroxyl group. This compound is critical for ensuring precise and efficient synthesis in complex pharmaceutical manufacturing processes. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and fine chemical sectors for the development and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs).
• Hormone Analog Research: Used in the research and development of novel estrogen receptor modulators and related therapeutic compounds.
• Process Chemistry: Employed in route scouting and optimization for the commercial production of complex steroid molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in regulatory submissions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	3-(Trimethylsiloxy)-1,3,5(10),9(11)-Estratetren-17-One
CAS No.	69833-95-0
Molecular Formula	C21H30O2Si
Molecular Weight	342.55 g/mol
Synonyms	3-(Trimethylsilyloxy)estra-1,3,5(10),9(11)-tetraen-17-one; 3-Trimethylsiloxyestra-1,3,5(10),9(11)-tetraen-17-one; Estra-1,3,5(10),9(11)-tetraene-3,17-diol, 3-(trimethylsilyl) ether, 17-one; 3-TMS-Estra-1,3,5(10),9(11)-tetraen-17-one; 3-(Trimethylsiloxy)-1,3,5(10),9(11)-estratetraen-17-one; 3-O-Trimethylsilyl-1,3,5(10),9(11)-estratetraen-17-one
EINECS	Contact for details

Quality Control

Our 3-(Trimethylsiloxy)-1,3,5(10),9(11)-Estratetren-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.