Description

3,6β,16α,17β-Tetrakis(Trimethylsiloxy)-1,3,5(10)-Estratriene is a high-purity, organosilicon-protected derivative of estradiol, designed for advanced synthetic chemistry applications. This compound is critical for researchers and manufacturers requiring a stable, non-polar intermediate for the precise synthesis of complex steroid analogs and pharmaceutical active ingredients. It is primarily utilized in pharmaceutical R&D, process chemistry, and the production of specialized fine chemicals where controlled functional group manipulation is essential.

Application

• Pharmaceutical Intermediate: A key protected synthon for the synthesis of novel steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism and developing new synthetic pathways.
• Process Chemistry: Serves as a stable intermediate in multi-step synthesis for scale-up and pilot plant production.
• Fine Chemical Synthesis: Employed in the manufacture of high-value, specialized steroid derivatives for various applications.
• Reference Standard: Can be used as a chromatographic or spectroscopic standard for quality control and analytical method development.

Basic Information

Product Name	3,6β,16α,17β-Tetrakis(Trimethylsiloxy)-1,3,5(10)-Estratriene
CAS No.	69833-54-1
Molecular Formula	C30H56O4Si4
Molecular Weight	585.06 g/mol
Synonyms	Estra-1,3,5(10)-triene-3,6β,16α,17β-tetrol, 3,6β,16α,17β-tetrakis(trimethylsilyl) ether; 3,6β,16α,17β-Tetrakis-O-(trimethylsilyl)estra-1,3,5(10)-triene-3,6β,16α,17β-tetrol; Tetrakis(trimethylsiloxy)estratriene; TMS-protected Estradiol Derivative; 69833-54-1; 3,6,16,17-Tetrakis(trimethylsiloxy)estra-1,3,5(10)-triene
EINECS	Contact for details

Quality Control

Every batch of 3,6β,16α,17β-Tetrakis(Trimethylsiloxy)-1,3,5(10)-Estratriene is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results including assay, purity, and identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.