Description

5-Bromo-1-Ethyl-1H-Indole-2,3-Dione is a brominated isatin derivative, a versatile and high-value heterocyclic building block. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-cancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Organic Synthesis Building Block: The reactive carbonyl and bromine substituents make it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized indole-based dyes and colorants.
• Biochemical Tool Compound: Employed in academic and industrial research to study enzyme inhibition and biological pathways.

Basic Information

Product Name	5-Bromo-1-Ethyl-1H-Indole-2,3-Dione
CAS No.	69736-76-1
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	5-Bromo-1-ethylisatin; 1-Ethyl-5-bromoisatin; 5-Bromo-1-ethylindoline-2,3-dione; 5-Bromo-1-ethyl-2,3-dihydro-1H-indole-2,3-dione; 69736-76-1; Isatin, 5-bromo-1-ethyl-; 5-Bromo-1-ethyl-1H-indole-2,3-dione
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Ethyl-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.