Description

(5Z,7E,22E)-3β-[(Chloromethyl)Dimethylsiloxy]-9,10-Secoergosta-5,7,22-Triene is a chemically modified secosteroid derivative, specifically a silyl-protected analog of a key vitamin D intermediate. This compound is of significant value in pharmaceutical research and development, serving as a crucial synthetic precursor for the production of novel vitamin D analogs and other high-value steroidal compounds. It is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of active pharmaceutical ingredients (APIs) for metabolic and bone-related therapies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of advanced vitamin D analogs and metabolites for clinical research.
• Chemical Research: Used in academic and industrial laboratories to study steroidal transformations and develop new synthetic methodologies.
• Fine Chemical Synthesis: Serves as a protected intermediate for the production of high-purity, specialized steroidal compounds.
• API Development: Employed in the development and scale-up of new Active Pharmaceutical Ingredients targeting vitamin D receptors.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic reference standard in analytical method development.

Basic Information

Product Name	(5Z,7E,22E)-3β-[(Chloromethyl)Dimethylsiloxy]-9,10-Secoergosta-5,7,22-Triene
CAS No.	69688-08-0
Molecular Formula	C31H51ClO2Si
Molecular Weight	515.28 g/mol
Synonyms	3β-[(Chloromethyl)dimethylsilyloxy]-9,10-secoergosta-5,7,22-triene; (5Z,7E,22E)-3β-[(Chloromethyl)dimethylsiloxy]-9,10-secoergosta-5,7,22-triene; Vitamin D3 Silyl Ether Derivative; 3β-[(Chloromethyl)dimethylsilyloxy]cholesta-5,7,22-triene; Secosteroid Silyl Ether Intermediate; CAS 69688-08-0
EINECS	Contact for details

Quality Control

Our (5Z,7E,22E)-3β-[(Chloromethyl)Dimethylsiloxy]-9,10-Secoergosta-5,7,22-Triene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Long-term storage is recommended at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.