Description

(R)-Methyl Oxazaborolidine is a chiral, non-racemic organoboron compound that serves as a highly effective asymmetric catalyst. Its primary value lies in enabling enantioselective synthesis, a critical process for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for research and industrial chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in carbonyl reduction and other key transformations.

Application

• Asymmetric Catalysis: As a chiral catalyst for the enantioselective reduction of prochiral ketones to produce optically active secondary alcohols.
• Pharmaceutical Intermediate Synthesis: Key reagent in the production of chiral drug candidates and active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of chiral ligands, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Process R&D: A valuable tool for methodological development and scale-up studies in asymmetric synthesis within research laboratories.
• Material Science: Potential applications in creating chiral polymers or frameworks with specific optical properties.

Basic Information

Product Name	(R)-Methyl Oxazaborolidine
CAS No.	69597-55-3
Molecular Formula	C4H8BNO
Molecular Weight	96.92 g/mol
Synonyms	(R)-2-Methyl-1,3,2-oxazaborolidine; (R)-2-Methyloxazaborolidine; (R)-Methyloxazaborolidine; (R)-MeCBS; (R)-CBS Catalyst; (R)-Corey-Bakshi-Shibata Catalyst; (R)-Tetrahydro-1-methyl-1H-1,3,2-benzodiazaborole; B-Methyloxazaborolidine (R)-
EINECS	Contact for details

Quality Control

Our (R)-Methyl Oxazaborolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (ee), and impurity profile. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/NMR)	≥ 95.0%
Enantiomeric Excess (ee)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.