Description

5-(2-Hydroxyethyl)-4-(Trifluoromethyl)Thiazole is a versatile heterocyclic building block characterized by its thiazole core functionalized with a hydroxyethyl side chain and a trifluoromethyl group. This compound matters for its unique combination of polarity, potential bioactivity, and the stability imparted by the fluorine atoms, making it a valuable intermediate in advanced synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, antibacterial, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a functional monomer or additive in the development of specialty polymers and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the nitrogen and sulfur donor atoms of the thiazole ring.
• Fluorine Chemistry Building Block: A valuable source of the -CF3 moiety for introducing fluorine into target molecules to modify their physicochemical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	5-(2-Hydroxyethyl)-4-(Trifluoromethyl)Thiazole
CAS No.	69439-09-4
Molecular Formula	C6H6F3NOS
Molecular Weight	197.18 g/mol
Synonyms	4-(Trifluoromethyl)-5-(2-hydroxyethyl)thiazole; 2-[4-(Trifluoromethyl)-1,3-thiazol-5-yl]ethanol; 5-(2-Hydroxyethyl)-4-trifluoromethylthiazole; 69439-09-4; Thiazole, 5-(2-hydroxyethyl)-4-(trifluoromethyl)-; 4-Trifluoromethyl-5-(2-hydroxyethyl)thiazole
EINECS	Contact for details

Quality Control

Our 5-(2-Hydroxyethyl)-4-(Trifluoromethyl)Thiazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.