Description

(1S,2S,3R,5S)-3-Amino-2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol is a high-purity, stereochemically defined bicyclic amino alcohol of significant interest in advanced organic synthesis. This compound serves as a versatile and critical chiral building block for the development of complex pharmaceutical intermediates and fine chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and functional complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic pathways.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity in critical bond-forming steps.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of complex fragrance compounds, flavors, and other high-value specialty chemicals requiring precise stereocontrol.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.
• Peptidomimetics & Bioactive Molecule Design: Its rigid bicyclic structure and functional groups make it suitable for constructing conformationally restricted scaffolds in drug discovery.

Basic Information

Product Name	(1S,2S,3R,5S)-3-Amino-2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol
CAS No.	69363-09-3
Molecular Formula	C10H19NO
Molecular Weight	169.26 g/mol
Synonyms	(-)-cis-Myrtanylamine; (1S,2S,3R,5S)-3-Amino-2-hydroxy-2,6,6-trimethylbicyclo[3.1.1]heptane; cis-3-Aminopinanol; (1S,2S,3R,5S)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol; (-)-cis-3-Aminopinanol; (1S,2S,3R,5S)-2-Hydroxy-2,6,6-trimethylbicyclo[3.1.1]heptan-3-amine; Pinane amino alcohol derivative
EINECS	Contact for details

Quality Control

Our (1S,2S,3R,5S)-3-Amino-2,6,6-Trimethylbicyclo[3.1.1]heptan-2-ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvent levels are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.