Description

Nedocromil is a synthetic chromone derivative and a mast cell stabilizer primarily used as an anti-inflammatory agent. Its core value proposition lies in its ability to inhibit the release of inflammatory mediators, making it a key active pharmaceutical ingredient (API) for managing respiratory conditions. This compound is essential for manufacturers in the global pharmaceutical industry developing preventative treatments for asthma and allergic disorders. We supply high-purity Nedocromil CAS NO 69049-73-6 to meet stringent pharmacopeial standards for API production.

Application

• Pharmaceutical API: Primary use as the active ingredient in inhalation aerosols, metered-dose inhalers (MDIs), and nasal sprays for asthma prophylaxis.
• Anti-allergic Formulations: Key component in ophthalmic solutions for the treatment of allergic conjunctivitis and other ocular allergies.
• Respiratory Research: Used as a reference standard and biochemical tool in preclinical research focused on mast cell biology and airway inflammation pathways.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing allergic respiratory conditions in animals.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control testing and method validation in analytical laboratories.

Basic Information

Product Name	Nedocromil
CAS No.	69049-73-6
Molecular Formula	C19H17NO7
Molecular Weight	371.34 g/mol
Synonyms	Nedocromil Sodium (salt form); Tilade® (brand name); Nedocromil Calcium; FPL 59002KP; 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-; 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our Nedocromil is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch is tested against rigorous specifications, including identity, purity, and impurity profiles, aligning with major pharmacopeial guidelines such as USP and EP. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place. Recommended storage temperature is between 15°C and 25°C. Ensure the storage area is well-ventilated and separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to greenish-yellow crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.