Description

4-Methyl-D1-Pyridine is a deuterated analog of 4-methylpyridine, where a hydrogen atom is replaced by a deuterium atom at the specified position. This isotopic labeling is critical for applications requiring precise molecular tracking and analysis, offering enhanced stability and distinct spectroscopic properties. It is an essential building block and analytical standard for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Research & Development: Used as a deuterated intermediate in the synthesis of labeled drug candidates for pharmacokinetic (ADME) studies, metabolic pathway tracing, and the development of deuterated drugs to enhance metabolic stability.
• Analytical Chemistry & Spectroscopy: Serves as an internal standard or reference material in quantitative NMR (qNMR), mass spectrometry (MS), and IR spectroscopy due to its distinct isotopic signature.
• Agrochemical Synthesis: Employed in the development of deuterated pesticides and herbicides to study environmental fate, degradation pathways, and to potentially improve efficacy.
• Material Science: Acts as a precursor or modifying agent in the synthesis of specialized polymers, liquid crystals, and organic electronic materials where isotopic purity can influence physical properties.
• Catalysis & Chemical Synthesis: Utilized in mechanistic studies of catalytic reactions and as a building block in fine chemical synthesis where deuterium incorporation is required.

Basic Information

Product Name	4-Methyl-D1-Pyridine
CAS No.	69046-49-7
Molecular Formula	C6H6DN
Molecular Weight	94.13 g/mol (for monodeuterated form)
Synonyms	4-Methylpyridine-d1; γ-Picoline-d1; 4-Picoline-d1; 4-Methylpyridine (methyl-d1); 4-(Methyl-d1)pyridine; 4-Methyl-d1-pyridine; Picoline-d1; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our 4-Methyl-D1-Pyridine is produced and tested under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive analysis including NMR for deuterium incorporation and GC/HPLC for chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting specifications for identity, purity, isotopic enrichment, and solvent residues.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are securely sealed. Recommended storage temperature is 2-8°C for long-term stability, although short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.