Description

[4-(Chloromethyl)-2-Thiazolyl] Guanidine Mono Hydrochloride is a high-purity, functionalized thiazole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical and agrochemical agents. It is primarily utilized by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate complex heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, or insecticides that require a functionalized thiazole core.
• Chemical Biology Research: Employed as a molecular scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Peptidomimetic Development: Acts as a building block for creating peptide analogs and mimetics with enhanced stability or biological activity.
• Ligand Synthesis for Catalysis: Utilized in the preparation of specialized ligands for metal-catalyzed reactions in fine chemical manufacturing.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific electronic or optical properties.

Basic Information

Product Name	[4-(Chloromethyl)-2-Thiazolyl] Guanidine Mono Hydrochloride
CAS No.	69014-12-6
Molecular Formula	C5H9Cl2N4S • HCl
Molecular Weight	245.58 g/mol (Free base: 209.12 g/mol)
Synonyms	1-[(4-Chloromethyl)-2-thiazolyl]guanidine hydrochloride; 2-(4-Chloromethyl-thiazol-2-yl)-guanidine hydrochloride; Guanidine, N-[4-(chloromethyl)-2-thiazolyl]-, monohydrochloride; (4-Chloromethyl-2-thiazolyl)guanidine HCl; 4-(Chloromethyl)-2-thiazolylguanidine hydrochloride; 2-Guanidino-4-(chloromethyl)thiazole hydrochloride
EINECS	Contact for details

Quality Control

Our [4-(Chloromethyl)-2-Thiazolyl] Guanidine Mono Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.